Derma E Advanced Peptides & Flora-Collagen Face Moisturizer, 2 Oz Review
A Derma E Advanced Peptides and Flora-Collagen face moisturizer, a 2 ounce vegan night cream built around a peptide complex, Pycnogenol and plant-derived Flora-Collagen, reporting a 6 week clinical trial with 100 percent of participants seeing improved skin elasticity.
| Brand | Derma E |
|---|---|
| Part number | 070824-KEHECA-1778 |
| Size | 2 oz |
| Formula type | Night moisturizer |
| Key actives | Pycnogenol, Flora-Collagen, Melatonin |
| Vegan | Yes, cruelty-free |
| Best for | Buyers wanting a vegan, peptide-based overnight moisturizer with reported clinical trial results |
Product Overview
Derma E builds this moisturizer around a peptide complex paired with plant-derived Flora-Collagen, aimed at an overnight routine that supports collagen health rather than a quick daytime hydration boost.
The brand backs the formula with reported clinical trial figures from a 6 week study, positioning the cream as more than a simple natural-ingredient moisturizer.
Score Breakdown
This verdict is based on the manufacturer's stated specifications, the current Amazon listing and its product images, the confirmed materials and design, real buyer ratings, and our research into the product category. Scores are consistent editorial judgments, not laboratory measurements, and we did not receive a paid sample.
Key Features
Supports collagen health and hydration lock-in.
Helps increase skin hydration.
Helps reduce signs of aging while fighting free radicals.
100% saw improved elasticity, 97% saw improved lines and firmness.
Free from parabens, sulfates, mineral oil and more.
Design and Build Quality
The formula carries part number 070824-KEHECA-1778 and ships in a 2 ounce jar, built around Pycnogenol for hydration, plant-derived Flora-Collagen to lock in moisture, and Melatonin to help fight free radicals and reduce visible signs of aging.
Derma E positions the brand itself around clean beauty: the formula is 100 percent vegan and cruelty-free, free of parabens, sulfates, mineral oil, petrolatum, lanolin, gluten, soy and GMOs, and supplied in recyclable packaging.
Performance in Everyday Use
The brand's reported 6 week clinical trial is the central performance claim: 100 percent of participants saw improved skin elasticity, 97 percent saw improved appearance of fine lines and wrinkles, 97 percent saw improved skin firmness, and 0 percent experienced irritation.
Application is intended for the evening, after thoroughly cleansing the face and neck, applying a rich layer and massaging gently until the cream is absorbed, in line with its positioning as an overnight repair product rather than a light daytime lotion.
How It Performs: The Evidence
| Decision factor | What we found | Evidence and measurement | Score | Why it matters |
|---|---|---|---|---|
| Elasticity improvement | 100% saw improvement | Listing states in a 6 week clinical trial 100% saw improved skin elasticity | 8.4 | Confirms the stated clinical trial result |
| Lines and wrinkles | 97% saw improvement | Listing states 97% saw improved appearance of fine lines and wrinkles | 8.2 | Confirms the stated trial result |
| Skin firmness | 97% saw improvement | Listing states 97% saw improved skin firmness | 8.2 | Confirms the stated trial result |
| Irritation rate | 0% experienced irritation | Listing states 0% experienced irritation | 8.5 | Confirms the stated tolerability result |
| Key actives | Pycnogenol, Flora-Collagen, Melatonin | Listing names these as the all-natural formula's active ingredients | 8.1 | Confirms the stated ingredient claims |
| Size | 2 oz | Listed size is 2 Ounce | 8.0 | Confirms the stated jar size |
Who Should Buy It
- Nighttime skincare routines
- Vegan and cruelty-free beauty preferences
- Buyers wanting a peptide and collagen-support formula
- Sensitive skin wanting a reported 0% irritation result
- Anyone wanting a daytime moisturizer with built-in sun protection
- Clinical trial figures are the brand's own reported results, not independent third-party testing of this specific jar
- Formulated as a night cream, so it is not positioned as a daytime SPF moisturizer
- The listing's own model field is left blank at 0, so no separate model number is available beyond the part number
- Sold in this single 2 ounce size on this listing
Full Specifications
How It Compares
| Feature | Derma E | Typical option | Higher-tier option |
|---|---|---|---|
| Formula focus | Peptide complex with Flora-Collagen and Melatonin | Single-ingredient basic moisturizer | Comparable peptide and collagen-support cream |
| Clinical reporting | 6 week trial with reported elasticity and firmness results | No clinical trial data provided | Comparable moisturizer with reported trial data |
| Formula ethics | Vegan, cruelty-free, no parabens or sulfates | Standard formula with common synthetic additives | Comparable vegan, cruelty-free moisturizer |
| Use time | Formulated as an overnight night cream | Daytime formula with SPF | Comparable night cream moisturizer |
| Packaging | Recyclable packaging | Standard, non-recyclable packaging | Comparable recyclable-packaged moisturizer |
Alternatives Worth a Look



A vegan, 2 ounce night moisturizer built around a peptide complex, Pycnogenol and Flora-Collagen, with a brand-reported 6 week clinical trial showing improved elasticity and firmness for most participants. It suits buyers wanting a clean-beauty overnight formula, with the main thing to know being these are manufacturer-reported results rather than independent testing.
Frequently Asked Questions
How is this moisturizer meant to be used?
As an overnight night cream, applied after cleansing in the evening.
What are the key ingredients?
Pycnogenol, plant-derived Flora-Collagen and Melatonin.
What did the clinical trial show?
Over 6 weeks, the brand reports 100% saw improved elasticity, 97% saw improved lines and wrinkles, 97% saw improved firmness and 0% experienced irritation.
Is it vegan?
Yes, 100% vegan and cruelty-free per the listing.
What size is the jar?
2 ounces, per the listing.
Does it contain parabens or sulfates?
No, the listing states it contains no parabens, sulfates, mineral oil, petrolatum, lanolin, gluten, soy or GMOs.
This review is based on the manufacturer's stated ingredients, reported clinical trial figures and packaging claims as listed. It is editorial analysis of the brand's own reported trial results, not independent third-party testing of this specific jar's effects on skin.